Top 5 Scientifically Proven Skincare Brands

NORDSTROM - New & Exclusive Bobbi Brown Eye Palette

affiliate link small

Do you ever spend a ton of money on a fancy-schmancy skincare product, only to find out it doesn’t do diddly-squat?  I have, and it pi$$es me off!  Luckily, this hasn’t happened to me in a LONG time, thanks to the fact that I now thoroughly research products before getting out my credit card.

Unfortunately, there are many brands out there that masquerade as being “clinical” in nature, and use bogus statistics in their marketing.  In my post, “Debunking Skincare Quack Ingredients: How Do You Find the Truth?” I go over some hints on how to spot the good stuff (read more here).

I often get questions regarding skincare products and what brands work best.  Well, the truth is, everyone’s skin is different, and there are SO many great brands out there.  This can be really confusing, so I’ve comprised a narrowed-down list of my top five brands that are dependable and backed by solid, proven science.

FYI- In the interest of giving you my real, true, honest opinion on what really works, I do NOT have an affiliate relationship with ANY of these brands.  While I am affiliated with several department stores and major retailers that may carry some of the products, I receive NO financial benefits from any of these five companies.

Bionova 11


Out of all the skincare brands out there, Bionova is the most unique.  The scientist in me gets excited every time I use something from them!  Their products are far different than any others on the market today.  Bionova’s skincare line is based on nanotechnology, and uses Hyper-Natural ingredients, meaning they mimic the substances that are naturally found in the human body.

Bionova skincare was founded by Dr. Michael Danielov, who is  an M.D., but also holds a Ph.D. in pathophysiology.  Not only was Dr. Danielov nominated for the USSR’s State Prize, the country’s highest award for science and technology, but he has done extensive research in the pathogenical mechanisms of thanatogeneses (mechanisms of death) of post-aggressive reactions in living organisms.  In other words, he knows a helluva lot about aging and what causes it!

As I mentioned, Bionova’s ingredients are Hyper-Natural.  Dr. Danielov’s research showed that everything the human body needs is already present.  Therefore, the best approach to modern skincare is to use substances that are natural to the body.  Since there is no introduction of foreign molecules, there are no side effects or adverse reactions, just fabulous results!

You can read more about Bionova here, and see my results here.  Additionally, Dr. Danielov’s research has been published in several issues of the Critical Care and Catastrophe Medicine Journal (numbers 4, 8, and 10).  You can read these articles on the publisher’s website,

Bionova products are available at Barney’s, Dermstore, and directly from Bionova.

Exuviance Sheer Daily Protector 1


Jerry and I both have our own separate Platinum memberships at Ulta, so we’re very familiar with Exuviance products, and have been happy with every product we’ve tried.

Exuviance was founded by Dr. Eugene J. Van Scott, a dermatologist, and Dr. Ruey J. Yu, a dermatopharmacologist.  The doctors were not only the first to patent alpha hydroxy acids in skincare, but they were also the first to bring us glycolic acid peels- much appreciated, Drs. Van Scott and Yu!  (You can read more here.)

Exuviance is also known for using polyhydroxy acids (versions of alpha hydroxy acids) that are less irritating, and can be used by those with sensitive skin.  Each of their products is formulated with ingredients that have been scientifically proven to be effective.

You can get Exuviance products at Ulta and directly from Exuviance.

Somme Institute A Bomb 1


I first heard of Somme Institute when an esthetician told me about the brand.  Somme Institute was founded by a team of dermatologists after they became disappointed with skincare products that didn’t perform up to their standards.

When I tried the Somme Institute regimen, I was very happy with the products- you can read about my experience here and here.  The company actually used FDA drug-like guidelines when conducting their research, which consisted of randomized, double-blind, placebo-controlled testing of their products.  So, believe me when I tell you, these people are legit!

Another impressive thing about Somme Institute is that they make their research available to their customers.  They actually sent me the methodology used in their testing, and documentation from peer reviews.  The research was validated by several industry heavy-weights, such as Albert Kligman, M.D., Ph.D., Professor of Dermatology, University of Pennsylvania School of Medicine, also known as “the father of Retin-A.”

Somme Institute skincare is available at Nordstrom, SpaceNK, and directly from Somme Institute.

Shop Space N.K. Now!



I was first introduced to Radical Skincare when Missy, at Shreveport’s (now Bossier City) Sephora, told me how awesome the Instant Revitalizing Mask was, so I tried it and LOVED it.

Radical Skincare was founded by two sisters whose father was a renowned doctor and pioneer in the anti-aging field.  Along with a team of chemists, Liz and Rachel Edlich created products for their own personal use.  You can read more about Radical Skincare here.

One of my favorite aspects of Radical Skincare is that while the products are very potent and physician-strength, they are formulated to be used by all skin types, including sensitive!  This is great for me because after using Retin-A, my skin has become hypersensitive.  I like that I can use products that are effective, yet non-irritating.

Radical Skincare is available at Nordstrom and directly from Radical Skincare.
NORDSTROM - Choose from 80+ FREE Gifts with Beauty Purchase



One of my all time favorite skincare products is Sunday Riley’s Good Genes Treatment, which utilizes lactic acid to brighten skin and reduce the signs of aging (read more here).

Sunday Riley reportedly bought her first wrinkle cream at the age of 12.  After working at cosmetic counters and getting a college degree in chemistry, she founded her namesake skincare line.

While Sunday Riley’s products are not advertised as all-natural, they are clean products with powerful active ingredients that actually work.  I’ve tried many of her products, such as the Bionic moisturizer, Start Over eye cream, and the Artemis face oil, but my favorites are the Good Genes Treatment and Ceramic Slip Cleanser, which you can combine to make a mask!

Sunday Riley skincare is available at Nordstrom and SpaceNK.

While this list is not all-inclusive, I’m hoping it will at least help in finding products that are worth your hard-earned money and that actually work!
NORDSTROM - Choose from 80+ FREE Gifts with Beauty Purchase

Have you ever wasted money on a product that didn’t work?  Have you tried any from the brands I listed?  What products are you interest in trying?  Scroll down to comment below!

Disclosure:  This post contains affiliate links.





  1. I got a Bionova cleanser in a gift with purchase set from Barneys and I really liked it!

  2. My spouse and I absolutely love your blog and find
    most of your post’s to be just what I’m looking for. Do you offer guest writers
    to write content for you? I wouldn’t mind producing a post or elaborating on a lot of
    the subjects you write regarding here. Again, awesome web site!

    Note- This comment contained an attribute which triggered the site’s spam filter. While the comment appears, all URLs, or other such links were automatically purged immediately upon entry, and there is no backlink for the comment author.

    • Hello! You’re more than welcome to contact us at, we’re currently running a special- for a very limited time, you can purchase a post for just $50! If you are interested in writing on our choice of topic, you can submit your curriculum vitae and links to your top 5 published works for consideration.

  3. I’ve tried the Good Genes and some of the makeup from Sunday Riley, but never any of the other brands. I never heard of Bionova and I’m most curious about it. I read some of the other posts and you said they had kits at the Dermstore, do you know if they still have them?

    • Hi Regina! Yep, they sure do! The kits will last a good while, too. I still have my Anti-Stress Care and N1-Custom, they are very concentrated and you don’t need to use much, so they last a LONG time. I’ve only had to re-order the cleanser and activator. I think you’ll really like the brand!

  4. I enjoy reading an article that will make men and women think.
    Also, many thanks for allowing for me to comment!

    Note- This comment contained an attribute which triggered the site’s spam filter. While the comment appears, all URLs, or other such links were automatically purged immediately upon entry, and there is no backlink for the comment author.

  5. I like Sunday Riley cashmere cleanser because it makes my skin real soft but I never tried the ceramic. Also I never heard of Some Insitute so I went to their website and it looks like they have some nice creams. Thanks for the info!

    • Hi Stellahhh! They sure do! Glad I could be of some assistance! 🙂

Comments are closed.